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Arthritis Pain Relief and the Cause of Arthritis
The next step in looking for solutions to your arthritis pain problem is to understand how arthritis works. Knowing more about arthritis will help you relieve your arthritis pain. Arthritis pain relief is the goal - understanding arthritis is the way to get there.
The Cause of Arthritis (osteoarthritis)The factors leading to the deterioration of cartilage in osteoarthritis is still not understood. Most experts now believe that osteoarthritis results from a genetic susceptibility that causes a biologic response to injuries to the joint, which leads to progressive deterioration of cartilage. Also, the ability to make repairs becomes limited as cartilage cells age. Aging Cells May be a Factor in ArthritisAlthough osteoarthritis generally accompanies aging, osteoarthritic cartilage is chemically different from normal aged cartilage. As chondrocytes (the cells that make up cartilage) age, they lose their ability to make repairs and produce more cartilage. This process may play an important role in the development and progression of osteoarthritis. Genetic Factors in ArthritisResearchers report a higher incidence of osteoarthritis between parents and children or between siblings than between husbands and wives. Genetic factors are thought to be involved in about 50% of osteoarthritis cases in the hands and hips and a somewhat lower percentage of cases in the knee. Inflammatory Response in ArthritisOne possible cause of arthritis is the inflammatory response due to the over-reaction of the immune system to an injury or other assault in the body, like an infection. This response causes cytokines, to gather in injured areas and cause inflammation and damage to body tissue and cells. It's known to play a role in rheumatoid arthritis and other muscle and joint problems associated with autoimmune diseases. But it's generally thought that inflammation plays a minor role in osteoarthritis and is more likely to be a result, not a cause, of arthritis. Injuries in ArthritisInjuries sometimes can be the start in the arthritic disease process. Osteoarthritis can develop years later even after a single traumatic injury to a joint or near a joint. Other Possible Causes of arthritisBleeding disorders, like hemophilia, that causes bleeding to occur in the joint.
Disorders, such as avascular necrosis, that block the blood supply closest to the joint.
Other complications of persistent, inflammatory arthritic conditions, like chronic gout, pseudogout, or rheumatoid arthritis. Conditions, like hemochromatosis, that cause iron build-up in the joints. I hope this information was helpful in understanding osteoarthritis (arthritis), and why arthritis pain sets in. It will help in your ongoing search for arthritis pain relief. It's important to stop this arthritic process to ward off the ongoing damage and resulting arthritis pain, makes one seek out arthritis pain relief. |
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